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Conformational stability of dimcric proteins: quantitative studies by equilibrium dcnaturation
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, limited to the active site), concern low-frequency collective modes below the sensitivity of the technique used and/or present only on a longer timescale (> 1 ns), and not directly related to fast thermal fluctuations
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The crystal structures of Ca^sup 2+^/CaM show an extended dumbbell shaped molecule, in which its two globular domains are connected with a long α-helix (1)
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Membrane binding of the G-protein subunits was followed by changes in the fluorescence of the CPM-labeled proteins (see Philip and Scarlata, 2004)
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After HDL de-lipidation by guanidinium hydrochloride (Gdm HCl), apoA-1, and apoA-2 were isolated by FPLC as described in Wetterau and Jonas (1982)
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30 BL; mean HL/BL=0
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Despite its high occurrence (78%), the salt bridge between CD4-K22(Nζ) and gp120-E429(Cδ) located at the edge of the interface of the molecular complex might be subject to fewer structural limitations than those in the center of the interface
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The use of solvent dye instead of the pigment may warrant investigation
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Females were randomly selected from each maturity stage observed each month and from as wide a range of ages as available (Table 2)
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4[degrees]C ire 1995-96, 1996-97, and 1997-98, respectively (http://co-ops
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1% Tween 20/PBS, and incubated with 4-chloro-1-naphthol solution (substrate of horseradish peroxidase in the kit) containing 0
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Extended and docked conformations of the hairpin ribozyme were also resolved and quantified in previous ensemble trFRET experiments (N
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Until now, convenience was missing from treatment options
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In 1999, Pharmacare drug expenditures on these groups were sizeable--about 86 percent of Pharmacare expenditures are on seniors (British Columbia Ministry of Health Services 2001)
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--Drug Discovery and Development Drug Regulatory Affairs M
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We also had tremendous input from advisory panels consisting of government, public and private organizations very knowledgeable with the new Drug Benefit and the Medicare population
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For the overall sample, there was a negative and significant (r = -0
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