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"We ended up with a program that undermines Medicare and costs way too much for a program with major gaps in coverage," said Roger Hickey, co-director of the Campaign for America's Future and a founder of Americans United, a coalition of consumer and labor groups demanding that Congress fix the plan
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The denatured state (the other half of the folding equation) and its role in protein stability
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Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17
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The stability of these mutants is ~3 kcal/mole lower relatively to the WT (20-22), and the internal flexibility of the polypeptide is considerably larger, particularly with I7S and F110S (18)
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Activity of the native batch (258 U/mg) was not significantly reduced by the neutron scattering experiments
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Target enzyme recognition by calmodulin: 2
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For prolate ellipsoids of this aspect ratio, the maximum packing fraction is ~0
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INTRODUCTIONHigh-density lipoproteins (HDLs) are heterogeneous complexes of lipids and specific proteins (termed exchangeable apolipoproteins) that mediate cholesterol removal from peripheral tissues to the liver via the process termed reverse cholesterol transport (Fielding and Fielding, 1995)
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Despite limited accuracy in the particle size determination and limited resolution, this system facilitates observation of lipoproteins, lipid-free and lipid-poor proteins on the same gel and is widely used for lipoprotein analysis (Davidson et al
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This suggests that the shape of the nuclei itself predetermines-in part-the fibrillar architecture of the amyloid
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, enable protofilaments to form fibrils (Jimenez et al
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Alzheimer's amyloid fibrils: structure and assembly
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For the final immunization, P
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8 × 10^sup 3^ s^sup -1^, respectively
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The surgery of the nasal septum is discussed with great clarity and detail
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They were expanded in monolayer culture, using medium supplemented with autologous serum, for approximately four weeks
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7 the opening of its 11th unit in an Eagan, Minn
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--Cell Biology and Biotechnology Health Psychology Pharmacy Administration Pharmaceutical Business (MBA) Bioinformatics Biomedical Writing MS
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com's Health Care Center for the latest news, views and analysis of technology's impact on health care
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com, which will be operated by pharmacy management systems provider PDX-NHIN, will open with the capability of handling 15,000 prescriptions per shift, according to July Kelley, senior vice president of Rx
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Low-level cable networks would even be invited
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. In essence, the structure consisted of an α-helix subdomain, which is a four-helix bundle, comprising α-helices 1-4; an α/β subdomain, comprising a β-sandwich, formed by a four-stranded parallel β-sheet (β-strands 1-4) and a three-stranded antiparallel β-sheet (β-strands 1, 5, and 6), and three short helices (α-helices 5-7) that contain the phosphorylation site (His^sup 186^) (Fig
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. but decreased as the temperature was raised (data not shown)
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. The presumptive phosphatidylserine receptor is dispensable for innate anti-inflammatory recognition and clearance of apoptotic cells
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. Smaller heating rates are related to larger red shifts
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. Table 1 shows the displacement errors at different rf pulse bandwidths and static magnetic field strengths for the chemical shift span of 5 ppm, the range which covers most of the signals relevant for in vivo ^sup 1^H MRS
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., in photosynthesis) to folding processes that can take minutes or longer (1)
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. NMR experiments in solution on RNase B and the proteinase inhibitor PMP-C (65,66) have shown that amide hydrogen exchange rates are correlated with the degree of glycosylation
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. ThT dramatically increases its fluorescence quantum yield when bound to amyloid fibrils; however, the mechanism behind this property is unknown
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. These components bound to native TTR have lifetimes of 2
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. The activation energy E^sub a^ was determined from the slope of these plots with the accuracy of 5-8 kcal/mol, which includes the fitting errors and the deviations among different data sets
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. In this case, the slow search for a specific binding site in d = 3 is substituted for a much more rapid diffusive search in d = 1 (along the DNA) by nonspecific binding of the repressor proteins
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.12 kJ K^sup -1^ mol^sup -1^; see Fig
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