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. An example of this comparison is shown in Fig
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. Asymmetry in the shapes of folded and denatured states of proteins
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. the accessibility of atoms and residues, the backbone dihedral angles, and the hydrogen bond and electrostatic networks of the protein
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. At physiological temperatures, atomic mean-square displacements (MSDs) measured by IENS reflect sampling of conformational substates (entropy) as well as vibrational amplitudes
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. Evidently increasing viscosity increases the quantum yield of DCVJ (Fig
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. Although less confined than CD4-F43, it is in close contact (In addition to the residues that are directly involved in intermolecular contacts or are in close proximity to the intermolecular interface, there are a few residues in gp120 that show large intraresidue entropy changes upon complexation (see Fig
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. Several are located in the putative trimerization interface, S243, C378, and 1439, and two of them, V255 and L260, are located in the β-turn that connects the inner and outer domains of gp120
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. At polymer concentrations below or above the LLPS concentration, crystallization occurs from a homogeneous solution, and there is an increase in crystallization temperature with polymer concentration
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. In EI^sup sc^, a single peak was observed in CD and DSC experiments, but in the pH range where the thermal transitions could be followed (pH 7-9), two different peaks were not observed; further, the T^sub m^ of the sole transition observed was pH-indcpendent between pH 7 and 9 (Fig
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. This is in agreement with MD simulation data: Modifications in the dynamics of large protein complexes relative to their component subunit are dominated by low-frequency collective modes which take place on the 10-ps range upwards (2,49), and may be invisible in the experimental space-time window chosen
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. 11c and c^sup /^)
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. In summary, both the kinetic (Fig
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. Human apolipoprotein A-I forms thermally stable complexes with anionic but not with zwitterionic phospholipids
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