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Probably the most famous inmate to witness Cash's first concert at San Quentin (1958) was Merle Haggard, who later, after receiving a full pardon from Governor Ronald Reagan, became a country-western singer himself
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' In return, leadership allowed a vote on the import proposal
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"Molten-globule" state accumulates in carbonic anhydrase folding
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Although the average shape in the EV limit is that of a prolate ellipsoid, the fluctuations in the R^sub g^ and δ-values are large
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They proposed that observations of residual structure need to be reconciled with the good solvent scaling law obeyed by denatured proteins
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Validity of the "two-state" hypothesis for conformational transitions for proteins
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Increasingly, researchers, manufacturers and consumers alike are delving into other benefits that dairy-derived proteins may provide
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For all heating rates the secondary structure elements (mainly α-helices) fully disappear and compared to GndHCl-induced unfolding (data not shown here) the CD signals are identical
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This has been shown to alter the conformational stability of HuBChE (35), and to raise stability against thermal denaturation by 10°C from 63 to 73°C (18)
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The CaM binding site coincides with the basic DNA-binding sequence of the bHLH dimers (11,15,16,17)
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The glass transition behavior of the globular protein bovine serum albumin
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Addition of 100 mM NaCl to the acid unfolded TTR monomers will immediately shield the positive charges and initiate a conformational change into a so-called A-state (Lai et al
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ApoA-1, apoA-2, and other exchangeable apolipoproteins have evolved from a common ancestor that is related to the smallest human apolipoprotein, apoC-1 (57 aa) (Luo et al
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Nascent HDL form discoidal particles comprised of cholesterol-containing phospholipid bilayer and the amphipathic protein helices that are wrapped around the disk circumference in a beltlike conformation (Lund-Katz et al
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Notochord flexion began at 6 mm and was complete by 7-8 mm BL
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Entropy calculations on a reversibly folding peptide: changes in solute free energy cannot explain folding behavior
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The average particle size increased with increasing dissolving temperature (step 2 in Figure 3) from a level of about 10-35 µm at 120 and 130°C to a level of about 40-65 µm at 140, 150, and 160°C
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Thus, it is not only important to use 130°C as the dissolving temperature, but also not to exceed this temperature significantly
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Stock assessments rarely consider changes in population age composition resulting from the removal of older age classes except to the extent that total egg and larval production is reduced
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And that's if he did everything by the book
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Then there's the convenience factor
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--Pharmaceutical Sciences* NEW JERSEYRutgers, the State University of New Jersey Ernest Mario School of Pharmacy M
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Analysts project sales to exceed $205 billion, with operating profits in excess of $15 billion
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. Movement between Helsinki and Stockholm was simpler after that
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. The excitation and emission wavelengths were fixed at 280 nm and 370 nm
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. Of particular interest is the value of R^sub o^, which is related to the persistence length and also provides a measure of the goodness of the solvent because R^sup 3^^sub o^ quantifies the average volume per residue set aside by the chain for interactions with the surrounding solvent (38,41)
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. Paramagnetic relaxation enhancement by nitroxide spin labels
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. Structure and stability of EI^sup SC^ in the presence of the effectors All the experiments in the presence of PEP and Mg^sup 2+^ were carried out at pH 7
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. We attempted, by docking of the EIN^sup sc^ and EIC^sup sc^ domains, to model the whole structure of EI^sup sc^ trying to keep the active-site histidine (in the EIN^sup sc^ domain) close to the PEP binding site (in the EIC^sup sc^ domain)
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. This sort of installation-as-a-world-in-miniature is a medium which has been used ingeniously by Mike Nelson, the artist who had his breakthrough show at Matt's in 2000
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. Hydrodynamic calculations can provide some indication as to the structural assignment of the internal motions identified from NMR relaxation experiments (see Supplementary Material)
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. This, in fact, is direct evidence supporting the model of amyloids as waterfilled nanotubes (Perutz et al
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.© 2005 by the Biophysical Society0006-3495/05/02/1344/10 $2
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. Put another way, the vast majority of the space covered by the energy landscape must actually be flat (on a scale of k^sub B^T) rather than funneled
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. In wet machining operations, a part is normally rough machined, then finish machined
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. For the hairpin ribozyme, the best fit to the donor decay was obtained using a model of two Gaussian donor-acceptor distance distributions, with mean distances of 34-37 [Angstrom] and 75-78 [Angstrom] (N
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. PhRMA doesn't dispute these estimates
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