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Many commercially important fish stocks, like the legendary Atlantic cod, are seriously depleted despite many years of federal and state regulation
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Spectra were averaged over three scans for each sample containing 3 µM GR in 30 mM HEPES, at pH 7
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In the case of rSBA, the derivative plot shows a minimum at 58°C, whereas in the case of gSBA the minimum is at 84°C
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The interactions between the attached glycans and the protein were assessed using the online LPC server (24)
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Our efforts based on use of the EV limit mirror the use of the hardsphere fluid as a reference state for van der Waals liquids (51,52)
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Polymer models of protein stability, folding, and interactions
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Formation of native and non-native interactions in ensembles of ACBP molecules from paramagnetic spin relaxation enhancement studies
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2 should not be considered a binding curve, it may still be instructive to estimate an apparent average affinity of ANS for the four azurin species
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Although for BSA a high binding capacity may be expected from its intrinsic tendency to bind nonpolar and aromatic moieties also in the liquid state, the above ANS binding data do suggest that beyond specific trends of individual polypeptides, multi-subunit proteins are more susceptible than monomers to destabilization and partial unfolding in the frozen state
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An alternative explanation is that in this concentration range, the presence of an interfacial layer of protein has a marked influence on the observed rheology
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We are grateful to Per Persson for initial assistance with electron microscopy work and to Jeffery Kelly and David Wemmer for providing the pmmHα plasmid
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Pyrene excimer fluorescence as a proximity probe for investigation of residual structure in the unfolded state of human carbonic anhydrase II
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This is of course a restatement of Levinthal's paradox (Levinthal, 1969; Karplus, 1997), but a helpful one, in that the two necessary assumptions for the paradox to arise are clearly seen
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The stabilizing interactions themselves may be either native or nonnative, in the latter case suggesting cases of tailored nonnative interactions
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Contact order, transition state placement and the refolding rates of single domain proteins
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Particle formation depends on various solution parameters and cooling conditions
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We inspected SEM images of printed silk, cotton, and rayon fabrics cured at three temperatures (150, 175, and 200°C) and a curing time of 3 minutes
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Winston Price, former president of the National Medical Association, clinical trials and drug research have focused on white males, which may contribute to health disparities among whites and other races
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In the case of cancer, Professor Croce points out that "All vertebrates are susceptible to cancer," and so they can be used as "natural experimental models" by meticulous observation of how the disease develops in them spontaneously in the natural environment (p
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Carmen Catizone, executive director of the National Association of Boards of Pharmacy, and Dennis Lyons, head of government and regulatory affairs for the Massachusetts College of Pharmacy and Health Sciences, aired their concerns over the Springfield importing program at a joint press conference at the Massachusetts State House Oct
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[ILLUSTRATION OMITTED]Wal-Mart's Ron Chomiuk, center, is flanked by (l to r) Brian Bradley, Doug Kavulich, Tom Johnson and John Cawlfield with Del Pharmaceuticals
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