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From his breakthrough Sun Records hits of the '50s to his unprecedented, Rick Rubin-helmed American Recordings (1994) renaissance, this box covers almost 50 years of songs that both explored and shaped the history of American music
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. * Hilton: We have targeted the big, ugly word "rework," with the goal of reducing our overall costs by 10 percent by next year
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. For example, the patient accounting department may have a goal of reducing the days in accounts receivable in the greater-than-90-day category
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. Get-ahead advice: "Financial preparation is key--have enough reserves so that losing a big client won't cripple your operations
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. Two intermediate states were populated at 2-3 M GdnHCl, as indicated by a combination of spectroscopic and chromatographic methods
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. , Champaign, IL) photon-counting spectrofluorometer
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. Jing-Tan Su, Sung-Hye Kim, and Yong-Bin Van State Key Laboratory of Biomembrane and Membrane Biotechnology, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing, China Submitted July 19, 2006, and accepted for publication October 11, 2006
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. To illustrate these points, we compare the values of P^sub oa^(r) obtained in the EV limit to those for three different models
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. Thermodynamics of dcnaturant-induced unfolding of a protein that exhibits variable two-state denaturation
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. Crystal structure of Escherichia coli malate synthase G complexed with magnesium and glyoxylate at 2
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. For most proteins, which typically bear more than one tryptophan, the observed emission spectrum is composed of multiple contributions of the five spectral classes
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. The pronounced blue shift for native proteins in NDSB solutions is most probably related to the fact that NDSB interacts with the surface of the proteins which causes a more hydrophobic nonpolar environment of surface exposed tryptophan residues
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. 4 B and comparison of the relative areas confirm that even on a mass basis the propensity to bind ANS, with the exception of BSA, is significantly larger for oligomers than for monomers
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. Acetylcholine receptors in the oocyte membrane
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. In contrast, binding of xenon in the four internal cavities of myoglobin was shown to reduce the overall protein B-factors by ~15% (13)
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. Percolation behavior of permeable and of adhesive spheres
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. The evident binding of these four different dyes to misfolded conformations of TTR indicates their potential use as tools for following the misfolding and aggregation process
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. , 1987), and the fact that insulin easily aggregates in vitro, have made the hormone an excellent model for protein aggregation studies (Nielsen et al
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. The compact mature fibrillar structures formed at the endpoint of the aggregation process may hence result from an effort to minimize the exposure of hydrophobic residues
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. Insulin at pH 2: structural analysis of the conditions promoting insulin fibre formation
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. For links to both of these articles, visit www
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. Although plain x-rays of the head (anteroposterior and lateral views) can adequately localize metallic fragments, CT is better suited to fully evaluating the course of a projectile and assessing the damage to surrounding soft tissue and bone
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. He adds that no stone is left unturned in the effort to hook suckers
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. That is, men are motivated to participate in gambling in different venues than women
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. According to Daniel Bernoulli (1738), the originator of the concept of utility, money has marginally decreasing utility; that is, when considering a series of constant monetary increments, the participantive value of each increment gets smaller and smaller
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. Swaisgood of North Carolina State University cite the use of phosphopeptides from casein fractions in dietary and pharmaceutical supplements and the possibility of tapping the antimicrobial properties of components like lactoferrin and glycomacropeptides as preservatives to promote consumer safety
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. In an attempt to correlate affinities and n values to specific aspects of the macromolecule, we observe that all mutants are less stable than the WT by a comparable amount, the denaturation-free energy change, ΔG° at 20°C, decreasing from 6-7 to ~3 kcal/mole (20,27)
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. The value of v estimated from measurements of the reduced viscosity of dilute solutions of BLG as a function of concentration or from the known dimensions of the dimer is in the range 3
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. The fluorescence intensity was registered by integration of the spectra to avoid adverse effects by spectral shifts
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. Some characteristic traits of the mature amyloid fibrils are the tendencies to bend, twist, and agglomerate
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. Careful double mutant studies would be required to identify such nonnative contributions unequivocally
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.After all of the players make their decisions, the dealer will flip over the final card and evaluate his or her own hand
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