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Collectively, we have worked with blind cave organisms for more than eighteen years, and one of us (Luis Espinasa) was working with blind cave fish in Jeffery's laboratory shortly after the publication of the momentous work on lens transplants
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Thermal unfolding of ribonuclease A in phosphate at neutral pH: deviations from two-state model
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A molecular dynamics study on universal properties of polymer chains in different solvent qualities
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As the SNR of NMR experiments increases with magnetic field strength, localized spectroscopy experiments at higher strengths could be promising because they could reduce the minimum detectable drug concentration in the cell
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According to the EDX analysis, neither Pb, Ag, nor Bi was detected along the solder/Cu or solder/Ni interface
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CPM-labeled proteins were excited at 385 nm and scanned from 420 to 540 nm
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Since lipid-free apoA-2 unfolds at much lower temperatures (Fig
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To quantitate the unfolding kinetics of apoA-2 on DMPC, we monitored the time course of the protein unfolding
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This permitted sufficiently accurate height determination (maximal vertical resolution was 0
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4 D), on the other hand, a smooth continuation at 8 ns of the configurational entropy buildup is observed when the complex trajectory is appended to the free one (solid line), whereas a slight stepwise increase is visible when the trajectories are appended in the reverse order (dashed line)
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However, the dissolving temperature was changed
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Grootendorst is also with the Department of Economics, McMaster University, Hamilton ON, Canada
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The CD-ROM contains data files, answers, and more material on advanced topics
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Other studies support the notion that DTC ads translate into prescriptions
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Its pharmacies alone average more than $3
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The mean physical component (PCS 12) HRQOL score for the entire sample was 51
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. This assignment is consistent with the previous results (24) and the predicted α/β structure of ACYI (17)
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. Interestingly, considerable conformational changes were observed before the enzyme was fully inactivated by high temperature
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. EI proteins are composed of two domains (6,7): a proteolytically inert N-terminal (EIN), and a proteolytically unstable C-terminal domain (EIC)
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. coelicolor, HPr^sup sc^, are different from those of the other members of the HPr family (17-19)
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. INTRODUCTION Most proteins are characterized by well-defined three-dimensional structures, which in general exist only within the limits of specific environmental conditions
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. Hence, for any reasonable value of Δ^sup ex^ (up to 6 ppm), these residues are in fast exchange (k^sup -1^^sub ex^ [much greater than] Δω^sub I^)
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. DNA compaction under such conditions can be considered as a model of DNA compaction in the protein-crowded environment inside living cells
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