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We have developed a method for analyzing ^sup 15^N-spin relaxation measured at two magnetic fields that corrects (τ^sup B^^sub m^)^sub app^ for internal motion up to ~4 ns, giving (τ^sup o^^sub m^)^sub app-corr^ (22) home improvement loan idaho .
From the distribution of (τ^sup o^^sub m^) values, the shape of the diffusion tensor can be determined (30), whereas the degree of anisotropy can be gauged from the maximum and minimum (τ^sup o^^sub m^)^sub app^ values home improvement loan idaho .
6, whereas Table 1 collects the data for residues with significant exchange broadening (see table legend for more details) home improvement loan idaho .
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CD melting curves of the apoA-2:DMPC disks show hysteresis at any scan rate, indicating intrinsic thermodynamic irreversibility of the transition (Fig home improvement loan idaho .
Therefore, throughout the following overnight dry incubation period no further structural transitions are likely to occur in the amyloid samples home improvement loan idaho .
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These fundamental aspects of RNA folding are frequently obscured by the strong tendency of RNA to form alternate secondary or tertiary structures, which act as kinetic traps and retard the overall rate of folding home improvement loan idaho .
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