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. For Trp residues in proteins, it is not uncommon to find average lifetimes that are significantly longer than for free Trp
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. Cavity statistics, P^sub oa^(r) folded ubiquitin are shown in Fig
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. 9, which plots the probabilities, P^sub oa^(r = U), of finding cavities of different sizes at the ensemble-averaged center-of-mass as a function of cavity radius a
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. Similarly, collectin family members, including mannose-binding lectin, surfactant protein (SP)-A, SP-D, and the collectin-like Clq, opsonize apoptotic cells with their globular heads, and then form a complex through their collagenous tails with phagocyte calreticulin and LRP
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. Possibly the dimeric nature of both the target and CaM overcomes the less specific hydrophobic interactions
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. In contrast, PLCβ^sub 2^ and its isolated PH domain, and the PLCβ chimera used here, binds to different membranes with little specificity (Wang et al
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. Thus, the initial state in the first jump was intact disks, and in the second jump it was a mixture of protein-containing vesicles and lipid-poor protein
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. Yet, this is precisely the insoluble, uncrystallizable character of amyloids that severely limits the number of applicable structure-determining methods, such as nuclear magnetic resonance, or x-ray diffraction
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. The energies were calculated every 5 ps as reported earlier by Hsu and Bonvin, 2004, and therefore N is 16,001 when analyzing the 2-10 ns simulation segments
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. , yolk or oil globule volume), and the size or health of eggs and larvae
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. Wyllie Echeverria (1987) observed similar timing far parturition of black rockfish off north-central California, with a peak in February but with parturition occurring through May
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. Using these simulations, we find that the shapes of the histograms are significantly altered by modest changes (twofold) in the interconversion rate constants or their ratio (equilibrium constant)
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. Exp Cell Res 1998:238:265-72
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. Further, the model was evaluated with PROCHECK (37)
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