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That this is indeed the case is shown by comparing cavity statistics in the EV limit to values obtained for freely rotating chains
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Compounds that alter the Rac-1/RhoA balance, by either increasing the level of active Rat-1 (preferable) or decreasing the levels and/or activity of RhoA/ Rho kinase, would be potential candidates for use in therapy
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To aid comparing the ANS binding propensity among the various proteins Table 2 lists the minimum number of binding sites (n) as well as the ratio n/Mw, normalization by the molecular weight taking into account that larger macromolecules, such as oligomers, have a greater probability to bind ANS simply for their larger mass
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Hence, R-type flux may not be suitable for efficient soldering with lead-free Sn-Ag-Cu-Bi solder
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Sample solutionsSolutions for microscopic observations were prepared by mixing PEG 3000 or PEG 10000 in twice-distilled water until dissolution, adding T4 DNA with further mixing and incubation for 30 min, adding DAPI with further mixing and incubation for 30 min, and finally adding alkali chloride solution and letting the sample solution sit for 1-2 h before observations
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The scan rate was tuned proportionally to the area scanned (from 500 nm × 500 nm to 10 µm × 10 µm) and was kept within the 0
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1 and then normalized by dividing it by the number of atoms of each residue
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Truncated variants of gp120 bind CD4 with high-affinity and suggest a minimum CD4 binding region
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Single-pair fluorescence resonance energy transfer on freely diffusing molecules: observation of Forster distance dependence and subpopulations
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Ratiometric single-molecule studies of freely diffusing biomolecules
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004) for the overall sample (r = -0
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. As a consequence the obtained transition temperatures are strongly depending on the heating rates (for a more extended discussion on this subject see (17))
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. We have developed a method for analyzing ^sup 15^N-spin relaxation measured at two magnetic fields that corrects (τ^sup B^^sub m^)^sub app^ for internal motion up to ~4 ns, giving (τ^sup o^^sub m^)^sub app-corr^ (22)
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. In PEG 10000, the concentrations of salts required to collapse DNA were about half those with PEG 3000
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.Generation of soluble prefibrillar aggregates of TTRTTR was dialyzed versus 10 mM HCl in dH2O (pH 2
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. Therefore, throughout the following overnight dry incubation period no further structural transitions are likely to occur in the amyloid samples
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