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Because cells that make up different parts of the eye come from different embryonic tissues, the transplanted lens must have activated genes in the cave fish's own cells
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The key to solving the protein-folding problem lies in an accurate description of the denatured state
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5 K for Mg^sup 2+^, -1
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2 mm^sup 3^), dried for two days at atmospheric pressure over silica gel, and weighed
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However, the present data cannot exclude internal motion involving reorientation of the CaM monomers, which have an excepted timescale of ~7-9 ns
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5 the protein conformation undergoes a reversible transition which leads to a swelling of the monomeric unit (29,30)
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, K^sub p^ ~ 70 as opposed to 10 µM; Philip and Scarlata, 2004)
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2 B); incubation for longer time (2
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The range of accessible quaternary fibrillar folds is not yet limited to these structural motifs, as the study on apolipoprotein C-II, which forms closed rings of amyloid (Hatters et al
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A new aspect is the formation of so-called superfibrillar aggregates as shown in Fig
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--Pharmaceutics Medicinal Chemistry Pharmacology Toxicology* UTAHUniversity of Utah College of Pharmacy Ph
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This type of effect has been observed i n situations in which there is only a fixed period of time to gamble (i
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. Zinc hydrolases: the mechanisms of zinc-dependent deacetylases
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. Earlier studies have shown that this protein shows exceptionally high stability in terms of free energy of unfolding when compared to other proteins from the same family
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. The studies show that there is no appreciable increase in the intensity of ANS fluorescence on dissociation to monomer or in the fully unfolded state (data not shown)
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. Hence, one can evaluate the extent of the intersubunit interactions due to glycosylation
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. This has been demonstrated by the generation of quantitative conformational propensities for a range of peptide sequences (48)
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.Address reprint requests to Suzanne Scarlata, E-mail: Suzanne
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.Disk fusion is accompanied by dissociation of lipid-poor monomolecular apoA-2, as indicated by the low-molecular-weight band corresponding to the particle size of ~7
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