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Structure and stability of EI^sup SC^ in the presence of the effectors All the experiments in the presence of PEP and Mg^sup 2+^ were carried out at pH 7
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) Encouraged by the rough agreement between the theoretical and experimental binding enthalpies, we aimed at extracting the binding entropy from our simulations and at gaining insight into CD4 binding-induced conformational changes in gp120 that are related to entropy changes
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