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. There is also anecdotal evidence that sighted people have keener nonvisual senses when they cannot see--remember how the nonvisual senses seem to come alive in a cave when the lights go out? Would blind people reorganize their neural networks better than eyed people, if both groups began living in the dark or inside a cave? That is a question our students, and readers, will have to ponder
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. The endotherm at pH 7 (Fig
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. In EI^sup sc^, although its sequence homology and its structure are similar to those of other EI proteins, the calorimetric equilibrium unfolding, as shown by DSC, is different
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. The fluorescence emission of the folded state is already rather blue shifted (λ^sub max^ = 327 nm), but also rather large λ^sub max^-values (341-344 nm) for the unfolded states contribute significantly to the large red shift
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. In particular differences in the extent of protein aggregation, in structural compactness, or simply in the structural arrangement of tryptophan residues in unfolded states can change the magnitude of the red shift observed during the unfolding transition significantly
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. laevis frogs were purchased from Xenopus I (Dexter, MI)
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. A relaxation-compensated Carr-Purcell-Meiboom-Gill sequence for characterizing chemical exchange by NMR spectroscopy
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. This work was supported in part by a grant-in-aid for the 21st Century COE "Center for Diversity and Universality in Physics" from the Ministry of Education, Culture, Sports, Science and Technology of Japan
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. In contrast to the large effects of pressure on the membrane interior, pressure does not appear to affect the membrane surface charge and has little effect on surface hydration (Rebecchi et al
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. The modeled structure of the EIC^sup sc^ monomer differed from that of EIC^sup tt^ (11) only in a deletion in the loop between α-helix 4 and β-strand 5, which is part of neither the active center nor the dimerization surface
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