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Hydration of apomyoglobin in native, molten globule, and unfolded states by using microwave dielectric spectroscopyKamei, TakashiABSTRACT The high resolution dielectric spectra of semidilute solutions of apomyoglobin in native (N, pH = 5), acid-- induced molten globule (A, pH = 4), and unfolded (U^sub A^, pH = 3) states have been measured in the range from 0 en home language loan texas .
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As can be seen in Fig en home language loan texas .
Generalized two-dimensional correlation method applications to infrared, Raman, and other types of spectroscopy en home language loan texas .
Hence, the first transition is related to the dissociation of the tetrameric unit to constituent monomers, whereas the second one represents opening up of the individual subunits en home language loan texas .
59^ scaling law is obeyed by both short and long chains (39) en home language loan texas .
EI proteins are composed of two domains (6,7): a proteolytically inert N-terminal (EIN), and a proteolytically unstable C-terminal domain (EIC) en home language loan texas .
Moreover, residues with significant exchange broadening are found en home language loan texas .
They can either be in fast exchange or in slow exchange to a lowly populated bound CaM state en home language loan texas .
Comparison of the unfolding rates and the melting data recorded by differential scanning calorimetry, CD, and light scattering indicates the rank order for the kinetic disk stability, apoA-1 > apoA-2 > apoC-1, that correlates with protein size rather than hydrophobicity en home language loan texas .
The "correctly folded" state of proteins: is it a metastable state? Angew en home language loan texas .
In this case the mutual diffusion of the helical and β-sheet portions of the protein is the dynamical process responsible for the gutter-like feature on the reduced folding surface en home language loan texas .
In contrast to the compact CD4, gp120 undergoes a number of significant loop contractions and translocations upon CD4 binding, which occur on a more extended timescale than the high-frequency local fluctuations en home language loan texas .
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