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Apparently, highly denatured states are to be viewed as embryos of native states since it is expected that native-like local and/or nonlocal signals are sampled with statistically significant probability in the denatured-state ensemble (10,130,131)
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Calculation of ensembles of structures representing the unfolded stale of an SH3 domain
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Arthritis Rheum 2002; 46:191-201(46) Firesteiu GS, Yeo M, Zvaifler NJ
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Our experiments demonstrate that in vivo localized MRS allows subcellular distinction in large cells noninvasively, evoking some legitimate hope for future applications to cellular systems of more typical dimensions
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The maximum wetting forces for Sn-Ag-Cu-Bi solder in comparison with Sn-Pb solder are shown in Fig
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2 and in Supplementary Material (Table S1)
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They generally have k^sup -1^^sub ex^ values below 100 µs confirming the trend
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A polyethylene glycol fraction (PEG 20-average molecular mass of 20 kDa) and silicone oil (200/500 cs) were obtained from VWR (Poole, UK)
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However, the off-rate of the association was too slow to be physiologically relevant (~2 min), suggesting that other cellular processes might serve to reduce the off-rate
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1 presents the progress of the spontaneous amyloidogenesis of insulin at 60° (left panel) and 70°C (right panel) monitored by time-lapse AFM
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, 2001b; Ahmad et al
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It is then fed to the cutting edge through ducts in the tool
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Heat dissipation without coolant requires a different approach to processing the part
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**********Many fish species in the North Pacific have a long reproductively active life span, which increases the likelihood of producing offspring during periods of favorable environmental conditions
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Role of secondary structure elements in tertiary foldingThe systematic study of hairpin ribozyme constructs containing different combinations of helical junction and loop elements presented here enables us to define the role of these secondary structural elements during tertiary folding
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Shapiro, MD, 62-132 CHS, Head and Neck Surgery, Mail Code 162418, UCLA School of Medicine, Los Angeles, CA 90095
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By contrast, limited type-II collagen staining was apparent in the pellets maintained in DMEM/10%FCS (Fig
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We can manipulate (1) to identify the effect of RP on the expected [DaysNSDPop
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We ran a regression of the form (1) to test whether Days[OpiatePop
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Such overdoses, which can lead to hepatotoxicity (liver damage), account for more than 60,000 hospital visits every year, and over 100,000 calls per year to the U
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