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. It is generally assumed that two distinct enzymes are involved in the intracellular degradation of N-acetylated proteins: the N-acetylated peptide hydrolase catalyzes the hydrolysis of the N-terminal amino acid residues from the N-acetylated proteins causing the release of acetylamino acids, which are finally hydrolyzed by ACYI (10,11)
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. The average shape of a denatured protein is that of a prolate ellipsoid We computed the ensemble-averaged asphericity values for each of the 23 sequences in the EV limit and the resultant data are shown as cross marks in Fig
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. That this is indeed the case is shown by comparing cavity statistics in the EV limit to values obtained for freely rotating chains
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. Exploring Flory's isolated-pair hypothesis: statistical mechanics of helix-coil transitions in polyalanine and the C-peptide from RNase A
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. We observed that at physiological pH as the concentration of protein was increased, the value of K^sub sv^ was reduced: 1
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- Claudia Rosett is a journalist-in-residence with the Foundation for Defense of Democracies
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. Denaluration and reactivation of dimeric human glutathione reductase
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. Conversely, side-chain moves lead to local conformational changes
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. Structural and dynamical properties of a denatured protein
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. Is there or isn't there? The case for (and against) residual structure in chemically denatured proteins
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. 1 C) between pH 7 and 8
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.ACKNOWLEDGEMENTSThe authors acknowledge the financial support provided by the Research Grant Council of Hong Kong for the project "Wetting Kinetics and Interfacial Interaction Behavior between Lead-Free Solders and Electroless Nickel Metallizations," CERG Project No
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