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Control experiments revealed a similar increase in thiol reactivity in the presence of 1 M KCl (data not shown)
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Two-dimensional infrared correlation spectroscopy study of the heat induced unfolding and aggregation process of Myoglobin
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Hence, not many orientations of the glycan chain upon attachment to the protein are possible and we assume that upon energy minimization, the structure obtained mimics the real situation
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1 kcal/mol for the first transition and 4
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Some efferocytosis receptors appear to perform primarily a tethering function by holding the apoptotic cell and phagocyte close together (eg, CD14 or CD31), (19,21,22) while other receptors are primarily involved with transducing the engulfment signal (eg, LRP and PS receptors [PSRs]), (11,21,23,24) hence the so-called tether-and-tickle hypothesis (Fig 1, top, A)
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Note that potential variation of the ^sup 15^N CSA between -150 and -200 ppm hardly affects RT^sup n^^sub 1^ (±3%), and thus does not affect the conclusions (22)
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Specific recognition of CD4 by gp120 is evidently the linchpin of the CD4-mediated viral infection pathway
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Briefly, fixed ovaries were manually manipulated and rinsed with water through a 1-mm square mesh sieve, which retained most of the connective tissue, into another sieve with 0
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. Besides, complex formation between GR and NADPH was only detected in the dimeric form of the enzyme, which would argue that NADPH does not participate directly in the process of GR folding/assembly
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. The remarkable size may result from both the number of monomers involved, and the fact that insulin aggregation intermediates are rather bulky and swollen with water (Dzwolak et al
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