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The reason that the autopeak at 1629 cm^sup -1^ did not appear might have been due to the overlapping of the adjacent intense peak at 1638 cm^sup -1^
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, glycans attached to subunit X forming hydrogen bonds with residues of subunit X), whereas the rest are intersubunit interactions
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The helix-loop-helix motif formed by the α-helix 9-α-helix 10 shows intermonomer salt bridges: Asp^sup 540^ in the motif with Arg^sup 422^' in α-helix 5 from the other monomer (the prime is used to designate residues in the other monomer)
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This feature can either by related to arising tyrosine emission (often observed around 305 nm for unfolded states when energy transfer to tryptophans disappears during a structural expansion of the protein; see, for example, Schmid (20)) or to elastic scattering caused by aggregation
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5 a, the transition temperature is nearly identical for samples with and without NDSB
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ThT dramatically increases its fluorescence quantum yield when bound to amyloid fibrils; however, the mechanism behind this property is unknown
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Specifically, focusing on the prefibrillar amorphous aggregates occurring 30 s after elevating temperature to the nucleation-enhancing 60°C, revealed the tendency of the globule-shaped oligomers to queue and assembly into elongated forms
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3A), small spots were evident along the lower jaw and the ventral part of the head
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Of these 91, 51 type-II eggs reacted with MT-1
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Exp Cell Res 1998:238:265-72
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2,295 2,071907 Kroger, Cincinnati3,413 1,750518 Safeway, Pleasanton, Calif
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