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HPLC analysisGR samples (5
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Although gSBA unfolded via a two-state process without the formation of any unfolding intermedialcs, the denaturation profile of rSBA was poputated with an intermediate (Fig
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For all other cases, the move is rejected
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Molecular dynamics simulations of the protein unfolding/folding reaction
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The S^sup 2^^sub s^ was either kept at a uniform constant value (M2I) or optimized together with τ^sub if^ and S^sup 2^^sub f^ (M2II)
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The fluorescence of ANS in the presence of unfolded TTR is minor and is completely silent for ThT
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In the first application of diffusion spFRET to study RNA folding, we have investigated the magnesium-induced tertiary folding of the hairpin ribozyme
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