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We hired an organization to facilitate the training program, which resulted in standardizing education across our organization
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. Michael Streissguth's Johnny Cash At Folsom Prison: The Making Of A Masterpiece is no ordinary biography of Cash, which has been done before: it's a survey of that performance, what led to it, and what came out of it, richly enhanced by the author's access to Folsom Prison and Columbia Record archives and illustrated with over 100 rare photos
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. The large-scale fluctuations that give rise to the contact density maps shown in Fig
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. Apparently, highly denatured states are to be viewed as embryos of native states since it is expected that native-like local and/or nonlocal signals are sampled with statistically significant probability in the denatured-state ensemble (10,130,131)
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. Sample preparation Before sample preparation, all protein stocks were dialyzed against 2 mM Hepes buffer, pH 7
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. Localized measurement of kinase activation in oocytes of Xenopus laevis
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. The influence of inhibitor-binding on global enzyme molecular dynamicsAlthough several studies using different techniques have shown a modification of global protein molecular dynamics on an Ångström-nanosecond scale upon inhibitor-binding, we were not able to detect any significant differences between the native and the inhibited HuBChE, at comparable degrees of hydration, up to ~334 K (61°C)
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. SUPPLEMENTARY MATERIALAn online supplement to this article can be found by visiting BJ Online at http://www
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. This analysis can potentially allow us to discriminate between A-state monomers, protein oligomers, and larger aggregates
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. Underlined items in the "Abundance" column indicatethat some or all of the specimens were preserved and at least oneindividual was correctly identified as Pseudopercis semifasciata
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. These data were fitted with a cooperative binding model, and the resulting fits are shown as solid lines in Fig
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. From 30°C to 50°C, no significant changes were observed tor the four components
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. Although the differences in the χ^sup 2^ residuals between M2II models with different τ^sub is^ are not statistically significant, it is safe to conclude that there is a slow timescale motion present with a correlation time of roughly 2
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. The AFM images of the mature amyloid at 70°C (Fig
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.--Medicinal Chemistry* OKLAHOMAUniversity of Oklahoma College of Pharmacy MS
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