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. All other reagents were of the highest analytical grade available
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. All properties characterized from simulated ensembles match predictions from rigorous field theories
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. This erroneous model is of interest only because it has been used previously for denatured proteins in studies aimed at correlating m values and ΔC^sub P^ to changes in solventaccessible surface area (90)
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. This increase in the helicity was further confirmed by the FTIR experiments carried out at pH 10 (Table 2)
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. The reaction rate is even slower above 24°C, suggesting that the heat-induced disk-to-vesicle conversion is thermodynamically irreversible
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. All other reagents were local products of analytical grade
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. The structural changes in this stage involved the partial unfolding of the solvent-exposed β-sheet structures and the transformation of about half of the Class I Trp fluorophores to Class II (see Fig
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