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So are we actually running out offish? "No," says Paul Rasp, a marine biologist with the National Oceanic and Atmospheric Administration (NOAA)
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. " But if that uncertainty opens the door to regulatory decisions that result in overfishing, the science, says Eagle, is sure on one point: "We know enough to know that there's trouble out there, and we ought to manage the fisheries accordingly
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. Implications for reconstitution of the active enzyme
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. Baseline correction was performed before the further analysis of the IR data
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. Topology, stability, sequence, and length: defining the determinants of two-state protein folding kinetics
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. Further, this modeled structure will make it possible to explain whether the structures alone can account for the differences in the thermodynamical parameters among the members of the family
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. 91 for diminazene and -0
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. To contribute to the ongoing discussion and to investigate the relationship among molecular dynamics, activity, inhibitor-binding, and unfolding, we carried out incoherent elastic neutron scattering experiments on two members of the cholinesterase (ChE) family: Tetrameric human butyrylcholinesterase (HuBChE), both native and covalently inhibited by the organophosphate nerve agent, soman (18), and dimeric native Drosophila melanogaster acetylcholinesterase (DmAChE)
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. That a two-contribution model is needed follows from a comparison of average experimental and theoretical R^sub 1^ values
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. Comparison of the viscous behavior with predictions from the Krieger-Dougherty equation indicates the hydrodynamic size of the protein decreases with increasing concentration, resulting in a slower approach to the glass transition than a hard sphere system
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. However, there has been no systematic investigation of the influence of the monocation nature on its ability to induce DNA compaction
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. To assess relative kinetic stability of the DMPC disks containing various apolipoproteins, we compared the rates of their thermal unfolding
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. First, some packaging materials allow UV light to pass through
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. During cleavage or ligation, the two loops are required to interact, which comes about through a magnesium-dependent folding transition that places the loops in close physical proximity (Murchie et al
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. The frequency of membrane/cytoplasmic immunoreactivity was semiquantitated using a 4-tiered (0, 1+ = 1% to 9%, 2+ = 10% to 49%, and 3+ = > or =50%) scoring scale
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. Before the introduction of RP, the restricted NSAID diclofenac was the most widely used NSAID; a year after Type 2 RP was introduced, however, rates of use dropped to about one-quarter of its pre-RP rate of use
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. 055 -227,6462,653 Acetaminophen/CodeineAverage monthly effect-302
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. NACB Laboratory Medicine Practice Guidelines: Recommendations for the Use of Laboratory Tests to Support Poisoned Patients Who Present to the Emergency Department
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- There were problems with setting the quotas, and the fishermen cheated
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. This indicates that subtle conformational changes are induced by low concentrations of GdnHCl (The existence of partially folded intermediate states in the unfolding of GR is indicated by a comparison of fluorescence spectral shift, anisotropy, iodide quenching, and CD data as a function of GdnHCl concentration
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. Exploring Flory's isolated-pair hypothesis: statistical mechanics of helix-coil transitions in polyalanine and the C-peptide from RNase A
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. Thermal denaturations following the ANS fluorescence did not show a native baseline, and a sigmoidal-like decreasing of the fluorescence was observed as the temperature was raised (data not shown)
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. The plateau level is preserved for DCVJ over 300 h, showing that this probe also binds to larger assemblies (spherical aggregates and protofibrils)
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. In the same way, if denaturant concentration affects the stability of the low-dimensional search spaces, or gutters, that are principally responsible for controlling the folding rate, then these experiments will also carry signatures of the search-structure
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.[FIGURES 1-3 OMITTED]Body pigmentation Argentine sandperch larvae were lightly pigmented during all stages of development (Fig
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.[FIGURE 10 OMITTED]An increase in absolute fecundity with age was observed in both prefertilization and postfertilization females, but they occurred at different rates
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. In striking contrast, neither the 2WJ nor the 3WJ ribozymes can populate such a high-FRET state in the absence of loop A
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