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Finally, given the role of GR in the maintenance of cellular redox state, preservation of a stable enzymatic capacity is likely to be very important for cell survival (under stress situations, in particular)
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the enzyme was more resistant to proteolysis (open and solid circles) (Fig
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Compact intermediate slates in protein folding
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5]-integrins, scavenger receptors, CD44, CD14, and complement receptors 3 and 4 (Fig 2)
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Among the several azurin mutants available, I7S, F110S, and C3A/C26A maintain a native-like fold (19,22) and will therefore present the same surface topology/chemical composition to the ice-water interface
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44 g/g), prepared as described above, but using H2O as the hydration medium rather than D^sub 2^O
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This new type of CaM interaction is the first example where two interacting CaM molecules interact with a dimeric target
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Identification of nanosecond-timescale internal motionThe presence of nanosecond-timescale motion can be directly identified from a plot of the normalized ratio of R^sub 1^ values measured at two magnetic fields (RT^sup n^^sub 1^) versus NOE (22)
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However, the off-rate of the association was too slow to be physiologically relevant (~2 min), suggesting that other cellular processes might serve to reduce the off-rate
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Membrane binding for PLCβ was determined by following the increase in acceptor fluorescence from PLCβ Trp donors to model membranes doped with 0
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In the triple-helix example that we looked at in detail, the nonnative hydrophobic strips that accelerate the final two-dimensional search are "activated" only when the helices themselves form, at least partially (by the formation of some native interactions) and when their axial rotational degrees of freedom align
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For this purpose each density value was standardized with respect to the maximum density observed for each survey season over all years
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Cheese could well be part of the solution
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2 B), where a subspace of the conformational space of the free molecule is sampled in the complex state
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)20Japan Sea-FarmingEarly 23 Apr '97Associationand late(Miyazu, Kyoto Pref
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Ratiometric measurement and identification of single diffusing molecules
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Reexpression of the differentiated chondrocyte phenotype requires a plasma/serum factor, replaceable by TGF-[beta] and blocked by EGF
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Items eligible for reimbursement include pain relievers, antacids, allergy and cold medicines, but not dietary supplements such as vitamins or toiletries such as toothpaste
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And Raman said he sees no reason to believe that drugstore
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We have put up with wasted tax dollars, broken families, swollen prisons, and swamped police forces
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. Immediately after the incubation, the protein samples were diluted 400 times with ultrapure hydrochloric acid in water (pH 1
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