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. The excitation wavelength was 285 nm and emission was measured at 315 nm
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. These result confirmed the previous assumption that the irreversible inactivation of ACYI at high temperatures might be due to protein aggregation (25)
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. Independently from producing evidence for the step-resolved character of the process, intermediate and morphologically heterogeneous forms were trapped and characterized, which yields direct evidence for the multipathway character of the amyloidogenesis of insulin
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. Transient association of newly synthesized unfolded proteins with the heat-shock GroEL protein
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. If the EV interactions, shown in Eq
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. Partial motivation for this reference line comes from the work of Zagrovic and Pande (78), who showed that internal distances in unfolded ensembles of several proteins follow the predictions of the ideal random-flight chain with link length of 3
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. The emission fluorescence spectrum of EI^sup sc^, by excitation at either 280 or 295 nm
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. 3, there is a statistically significant improvement in χ^sup 2^ for the vast majority of CaM N-H^sup N^ backbone vectors when a second internal correlation time is introduced
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. Osmotic equilibria in solutions of serum albumin and sodium chloride
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. DCVJ bound to the early prefibrillar oligomers (300-500 kD) with an apparent dissociation constant of 1
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. Plasma levels of HDL and apoA-1 correlate inversely with the incidence of coronary artery disease, yet the role of the second major HDL protein, apoA-2, is less clear (Hedrick and Lusis, 1994; Blanco-Vaca et al
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. The atoms of each residue (code: res); see Fig
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. All that, and more, preceded the Gulf War in 1991, which led to a massive expansion of the U
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