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. We find that residues with significant exchange broadening (Table 1) group in a model structure of the CaM:SEF2-1mp complex into three regions: i), the CaM dimerization interface, i
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. We have found that for membranes composed of lipids with electrically neutral or negatively charged head groups, no change in surface charge could be detected at neutral pH from 1 to 2000 bar
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. The bridging sheet of gp120 also plays a key role in the entropy change, as has been proposed experimentally (Myszka et al
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. Evidence for a unique folding intermediate in the 4WJ ribozymeOur results indicate that the SL 4WJ ribozyme can fold into a compact conformation in the presence of high Mg^sup 2+^ concentrations, with arms A and B juxtaposed in a similar fashion to the docked native 4WJ ribozyme
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. For all heating rates the secondary structure elements (mainly α-helices) fully disappear and compared to GndHCl-induced unfolding (data not shown here) the CD signals are identical
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.07, and are fairly uniform throughout the sequence, except for five outliers with S^sup 2^^sub s^ values between 0
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.Dynamics on micro- to millisecond timescaleThree different approaches were used to determine which CaM residues in the CaM:SEF2-1mp complex are affected by conformational exchange
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. The exchange data for all residues are summarized in Fig
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